Bioprocesses

Inline analysis in bioprocesses

Observe cells, aggregates, and bubbles throughout cultivation.

Bioprocesses and bioreactors
The challenge

Samples capture moments; cultures change between them.

Samples capture moments; cultures change between them. In situ images follow populations and morphology in the actual environment.

01

CHO cells and aggregates

02

Yeast, budding, and morphology

03

Fungi, filaments, and pellets

04

Bubble size and population

Visual results

Microorganisms and cells captured in culture media.

Microorganisms and cells captured in culture media. 1
CHO cells and aggregates
Microorganisms and cells captured in culture media. 2
Yeast, budding, and morphology
Microorganisms and cells captured in culture media. 3
Fungi, filaments, and pellets
From objects to data

Continuous information that reveals change.

01

Size and distribution

02

Count and population

03

Shape and morphology

04

Real-time trends

Technology and application

SOPAT: in situ microscopy in the bioreactor.

Optics are selected for organism, density, size, agitation, bubbles, sterilization, and vessel access.

Technical note: Available variables depend on organism, contrast, concentration, optics, and algorithm validation.

Technical questions

Frequently asked questions about this application.

Can CHO cells be observed without sampling?

Yes, depending on density, vessel access, and optics.

Can it detect fungi and yeast?

Application materials show yeast and filamentous morphologies; each organism requires assessment.

Can it measure bubbles?

Yes, using an appropriate configuration for size, shape, and population.

Technology and application

Let’s assess your process conditions.

Tell us the product, expected range, concentration, available point, and measurement objective.

Request a technical assessment